Mutant Mindframe is the only solo release from Big Gipp, of Goodie Mob fame, recorded during his short stint away from the group. It was released in 2003 under Koch Records for Gipp to express his other-worldy musical inclinations that didn't fit with Goodie Mob's Southern lifestyle, conscious message. He calls on the lyrical help of many of his Dungeon Family-affiliates. Contributors include the new rapper Gator, R&B crooner Sleepy Brown, Slimm Calhoun, Andre 3000 of OutKast, 8Ball, Witchdoctor, Big Rube, and fellow Goodie Mobbsters T-Mo and Khujo. Mystikal, Too Short & RZA were also supposed to contribute to the album, but didn't make the cut.
In the CD booklet, Gipp gives the following words of advice: